Environmental estrogens exposure (cellular reproductive foreclosure)

from For the sake of reproducibility - a technical replicate by Tumor Necrosis Factor-alpha

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Enhanced levels of estrogens in the context of the cellular neurogenesis machinery
Brain development compromised with paracrine signals and unwarranted apoptosis activity
Abnormal development of oestrogeno-dependent reproductive physiological functions
Induced by environmental traces of oestrogen-like chemical contaminations

Environmental estrogens exposure - cellular reproductive foreclosure

Early life exposure to micro-levels of hormone-mimicking toxic pollutants
Leading to a higher incidence of reproductive failures and neurobehavioral mutants
Irreversible epigenetic reprogramming induced by early life exposure to environmental estrogens
Ovarian follicular developmental dysfunction putting a halt to normal reproductive functions

Environmental estrogens exposure - cellular reproductive foreclosure

Chemical contaminants causing the disruption of the estrogen signaling pathway
Endocrine disruptors, abnormal ovarian development is underway

Ref: Cruz G et al. “Long-term effects of early life exposure to environmental estrogens on ovarian function: Role of epigenetics.” J Neuroendocrinol. 26(9): 613-24 (2014)

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from For the sake of reproducibility - a technical replicate, released January 24, 2018

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Tumor Necrosis Factor-alpha Neuville, Québec

Scientists, academics, gorefiends and grindheads of the world rejoice: Tumor Necrosis Factor-alpha unleashes its take on full blown Carcass-worship, topped with unique lyrical themes inspired by the most recent knowledge in state-of-the-art scientific research from the fields of cellular and molecular biology. ... more

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